PharmDB-K is composed of nine different relationship categories,
namely TKM-Disease, TKM-Drug, TKM-Protein, Drug-Disease, Drug-Drug,
Drug-Protein, Drug-Side Effect, Disease-Protein and Protein-Protein.
We categorized FDA approved drugs and all types of chemicals
including experimental compounds, indicator and ingredient compounds
of herbs into Drug because of its possibility.
So, TKM-Drug relationship mainly means indicator compounds,
active compounds and chemical profiles of herbs.
The data was imported from fourteen different databases (ChEMBL, CTD,
DCDB, DIP, DrugBank, Entrez Gene Interactions, GAD, Korean Traditional
Knowledge Portal, MATADOR, MINT, OMIM, SIDER, T3DB and TTD)
and six Pharmacopoeias and published articles. For data integration
in a unified format, we adopted PubChem CID for drugs,
Entrez Gene ID for proteins, MeSH descriptor for diseases and side effects,
and Med CD number of Korean Traditional Knowledge Portal for herbs.
PharmDB-K was designed to introduce TKM to cutting edge drug discovery
research field. We believe that PharmDB-K provides new insights
of TKM-originated drug development research.